| Name | Analyse | Technik | Material |
| EndoPredict | 11-Gen-Assay |
q-RT-PCR |
FFPE |
| Mammaprint | 70-Gen-Assay |
DNA Microarrays |
frisch eingefroren |
| Oncotype DX | 21-Gen-Assay |
q-RT-PCR |
FFPE |
| Theros | 2-Gen-Ratio HOXB 13 IL7R |
q-RT-PCR |
FFPE |
| MapQuant | Genomisches Grading |
DNA Microarrays |
frisch eingefroren |
| PAM 50 | 50-Gen-Assay |
q-RT-PCR |
FFPE |
Formalin-fixiert Paraffin-Einbettung
| BRCA2 | 1.89 | |
| BRCA1 | 1.84 | |
| CHEK2 | 1.08 | |
| ATM | 0.82 | |
| PALB2 | 0.78 | |
| BRIP1 | 0.24 | |
| PMS2 | 0.18 | |
| BARD1 | 0.17 | |
| TP53 | 0.16 | |
| RAD50 | 0.16 | |
| MSH6 | 0.15 | |
| NBN | 0.14 | |
| RAD51C | 0.12 | |
| NF1 | 0.10 | |
| MRE11A | 0.08 | |
| MSH2 | 0.07 | |
| PTEN | 0.07 | |
| CDH1 | 0.06 | |
| 0.05 | ||
| CDKN2A | 0.05 | |
| MLH1 | 0.05 | |
| APC | 0.03 |
Teil von
A study of over 35,000 women with breast cancer tested with a 25-gene panel of hereditary cancer genes.
Cancer 2017;123:1721-1730
2.) Couch FJ, Shimelis H, Hu C, et al.:
Associations between cancer predisposition testing panel genes and breast cancer.
JAMA Oncol 2017;3:1190-1196